Prednisolone 5mg TabletsPrednisolone 5mg is a prescription corticosteroid medication used primarily to reduce severe inflammation, calm an overactive immune system, and treat various inflammatory and autoimmune conditions. It works by mimicking cortisol, a natural hormone produced by the adrenal glands that helps regulate stress and metabolism. Primary Medical Uses Doctors prescribe prednisolone to treat a wide variety of medical issues, including: Respiratory Conditions: